Florence Gazeau (1970) obtained her Ph.D. in solid state physics from the University Paris 7- Diderot in 1997, focusing on the magnetic and hydrodynamic properties of ferrofluids. She joined the National Research Center for Scientific Research (“CNRS”) as a staff scientist in 1998, when she broadened her research on biomedical applications of magnetic nanoparticles. Her current research interests focus on the physics of nanomagnetism applied to nanomedicine, cell-nanoparticles interactions, cellular MRI, nanoparticles-mediated hyperthermia, magnetic targeting, nanoparticles behavior, biodegradation and long term in vivo fate and nanotoxicology.
She is also developing alternatives to cell therapy by extracellular vesicles as a novel class of drug delivery system. She is a senior CNRS scientist (DR2) since 2009, and she works in the laboratory Matière et Systèmes Complexes at the University Paris Diderot. She is animator of the group Nanomedicine at the French observatoire of micro and nanotechnology. She is authors of more than 117 publications.
Biophysicist affiliated to the Condensed Matter section of the CNRS, has oriented her research to the biomedical field since obtaining her PhD in 2002. Her works during this last decade lied at the crossroads of magnetism, biophysics and nanomedicine and were resolutely multidisciplinary, taking advantage of the physical properties of magnetic nanoparticles to develop more effective treatments and new methods of medical investigation. She was appointed CNRS research director in 2013, she received the CNRS bronze medal in 2011, and the Louis Ancel prize in 2014.
I obtained a degree in Pharmacy in 2005 and a PhD in Pharmaceutical Technology in 2008 both from UFRN, Natal, Brazil. My thesis was in the domain of gastro-resistant magnetic microcapsules. I obtained a second PhD in Cellular and Molecular Biology in 2010 concerning polysaccharides for thermo-controlled cell culture at Université d’Evry/Université Paris V, France. I worked as a postdoctoral fellow at Université Paris Diderot on drug-loaded magnetic nancoarriers of cell origin (nanovesicles).
My second post-doc was carried out at Inserm U698 in Paris involving the development of nanosystems for atherothrombosis therapy. I am currently a CNRS researcher and I am interested on cell-derived vesicles for drug/nanoparticle delivery and regenerative medicine.
I am a Biochemist and molecular Biologist. Since I am in a multidisciplinar lab, I have developped projects at the interface of Biophysic and tissue engineering. My current researchs focus on metal nanoparticle degradation by cells and cartilage tissue engineering.
After a PhD in physics obtained in 2007 concerning membrane protein interactions at ENS Paris, I joined the group of Pascal Silberzan at Institut Curie to work on collective cell migration and the interplay of mechanical forces and Rho-GTPases activity. Since 2011 I am an assistant professor at Université Paris Diderot and I am interested in tissue mechanics. My two main ongoing projects are focused on the rheology of biological tissue using multicellular magnetic aggregates and on the engineering of an artificial muscle tissue.
I am a third year PhD student in the PIF doctoral school. I am a chemist by training and i’m very interested by the interaction biology-chemistry. I’m working on the degradation and the biotransformation of inorganic nanoparticles in the cell and in vivo.
I am a first year PhD student, originally from Spain. I studied a BSc in Biotechnology in the Politechnic Universtiy of Valencia and then came to Paris to do a Masters in Biomedical Engineering, specialising in the area of Biomaterials. My PhD projects aims to develop therapeutic systems for the delivery of nanoparticles and therapeutic molecules for combined photothermal and inmunotherapy in tumoral tissue combined with the evaluation of the changes of the mechanical properties of the extracellular matrix in the microenvironment of the tumor after these therapies.
After a master degree in materials chemistry, I joint the MSC for a project at the interface of chemistry, physics and biology: understanding the fate of nanoparticles in an intracellular medium. For this project, we focus on the influence a cell has on the physicochemical properties of gold nanoparticles, and how these low-reactive compounds can impact the cell and particularly its degradation capacity.
After a degree in biotechnologies at the ESPCI Paris and a Master 2 of Biophysics at the University Paris Diderot, I decided to continue my path in the scientific world by doing a PhD in Biophyscis. I started my PhD programm on October 2016 on tissue engineering at the MSC laboratoty under the supervision of Claire Wilhelm and Myriam Reffay. The aim of the project is to use magnetised cells to create and organise 3D tissues.
After the master's degree in Medical Biotechnology at Federico II Naples University in 2009, I obtained the PhD in Nanosciences at the Istituto Italiano di Tecnologia of Genoa in the Dr. Teresa Pellegrino's group of Nanomaterials for Biomedicine in 2013, focusing on stimuli-responsive organic/inorganic nanostructures for controlled gene and drug delivery.
I worked as postdoctoral fellow in the same group until 2015 studying magnetic and plasmonic nanoparticles functionalized with biomolecules for hyperthermia cancer therapy. In 2016 I started my second postdoc concerning the development of magneto-plasmonics nano-assembly nanoparticles for multimodal cancer therapy at the Université Pierre et Marie Curie in collaboration with Prof. Ali Abou-Hassan and Dr. Claire Wilhelm and now I am currently working in her group at Paris Diderot on the characterization of magneto-plasmonic nanoparticles in different murine cancer models.
I am a PhD student working on the fate of inorganic nanoparticles once internalised into cells. With in vitro models, I study the long-term biodegradation of nanoparticles but also the impact of the intracellular confinement on the therapeutic properties of the particles.
I have a technician background on Bioanalysis and Control obtained at École National de Chimie de Biologie etPhysique, in Paris. I obtained then a degree in Biotechnologies and Bio-industries in 2015 at Université Paris-Saclay in Orsay. Since then, I have worked on laboratorial quality control for biotherapies and GMP bio-processes.
I obtained a master’s degree in botechnology in 2017 at the University of Montpellier. After several experiences in upstream bioprocess on micro algae and bacteria systems, I joined the BioTher team and I'm working on thematic of Extracellular vesicles. At the edge of Biophysics, my project is focused on a innovative production approach of these vesicles by human stem cells, to use as bio-vectors for various therapeutic molecules.
After a physics degree at Université de la Méditerranée Aix-Marseille II in 2010, Iris obtained a Master degree and a PhD in Biophysics in 2012 and 2015, respectively, at Université Paris Diderot. After a post-doc at CNRS/Gustave Roussy Hospital on biophysics, Iris joined the BioTher team where she works on extracellular vesicles for regenerative medicine.
After three years at ESPCI Paris, I chose to do the Biomedical Engineering Master of Paris Descartes with a specialisation in Biomaterials. I joined the team for my M2 internship, during which I worked closely with Max on a revolutionary new method of producing extracellular vesicles. I am now doing a PhD, trying to decipher the mechanisms behind this high yield production method and developing the loading of extracellular vesicles with nanoparticles and chemicals.
After a master's degree in bioengineering, I did a PhD in nanotechnology. This project focused on developing new contrast agents for molecular imaging of cancers using iron oxide nanoparticles and targeting molecules. As nanoparticles are also promising tools in regenerative medicine, I joined the MSC laboratory for a post-doctoral project to develop a new magnetic approach for the cardiac tissue engineering.
Graduated in Physics, I obtained my PhD in 2010 at the University Autónoma of Madrid (Spain). The research was devoted to the study and fabrication of heterostructures and thin films based on wide band gap oxides for applications in Information Technologies. I worked as a postdoctoral fellow at the Magnetism and Magnetotransport Laboratory (ICMM-CSIC, Spain) on the study of structural and magnetic properties of nanoparticle systems, in particular iron oxide nanoparticles for biomedical applications, ZnO nanoparticles coated with organic molecules and cobalt based-nanoparticle systems embedded in amorphous matrix for spintronic devices.
In 2013, I joined the Laboratoire de Matière et Systèmes Complexes (MSC, France) to conduct a research activity based on nanotherapies for cancer treatment by means of thermal effect (magnetic and plasmonic hyperthermia). In 2014, I was granted with a Marie Curie Fellowship IEF within the project DUALNANOTHER, devoted to the evaluation of therapeutic potential of combined hyperthermia for cancer treatment. Currently, my research activity is focused on the impact of bio-induced interactions and intracellular degradation for magnetic nanomaterials embedded in tissues.
After graduating with a PhD in biomedical engineering from the University of Florida (2015), I joined the MSC laboratory at the University Paris Diderot as a Postdoctoral Fellow. My current work combines tissue engineering strategies with innovative magnetic nanoparticles technologies developed at MSC and that present a high potential for regenerative medicine applications. The main goal of my project is to produce articular cartilage replacements for the repair of osteoarthritic defects.
Dan Elgrabli is a doctor of toxicology, clinical pharmacology and drug’s mechanism. After his PhD dedicated to the study of carbon nanotubes toxicity due to hopes they inspire in medicine, he leads scientific projects in the field of nanotoxicology at INERIS (National Institute for Environmental protection and Industrial Risks Management). After this experience, he joined l’Oreal where he participated to the defense of new innovative products and safety assessment. Then, he joined Addenfi, a biotechnological company, as Deputy Director and Scientific Officer.
He currently developed research instruments and research activities as a CRO in the areas of pharmacology and toxicology. Its responsibilities lead him to manage a team, developed new methods in the laboratory, coordinate and assess projects in the field of toxicology. To focus on the use of carbon nanotubes as therapeutics agent, he joined MSC laboratory to better understand the life cycle of this nanoparticules and its interaction with macrophages for pharmacological applications.
After begining the first years of medical studies in Dijon, I discovered that it was possible to make both research and medicine joning the "Ecole de l'INSERM Lilliane-Bettencourt". I began studying biology and hematology, but swithched to biophysics right after Dr F. Amblard's course, and joined the MSC Lab and the "Centre de Recherche Interdisciplinaire". Now, my project aims at designing new kind of drug delivery vectors by hacking Mother Nature's communication pathways : using extracellular vesicles as a carrier for nucleic acids, viruses or drugs, and explore their use in regenerative medicine.
Graduated from Havana University in 2006, I have developed abilities in cancer & cancer immunology & immunotherapy research throughout my entire work and academic experiences in the past 10 years. Working in tight relation with clinicians, I monitored the vaccine-induced immune response and tumor biology of cancer patients enrolled in variety clinical trials. Concomitantly, I have got trained in many immunological techniques and clinical trials procedures along with an exhaustive cancer & tumor immunology theoretical learning due to frequent seminars and workshops.
The involvement in clinical trial studies endowed me with communication skills enough to
and cooperative research. As part of my work, I headed for several months the laboratory I
was working at,
and, was the organizer of the First International Workshop on Clinical Cancer Immunotherapy
in Havana, November
2009, under the auspices of UICC. Since January 2011, I worked during a PhD program (UAM-La
PhD Program) in cancer nanotechnology at National Center for Biotechnology where I
consolidated my research
skills applied to the development of new cancer-targeted gene therapy, specifically,
gene therapy. I consistently studied the interaction of nanomaterials with
reticulo-endothelial system and tumor
cells, providing new knowledge on the field. During this period, I learned a wide variety of
chemical synthesis, chemical and physical characterization of nanoparticles, cell culture,
molecular biology (qRT-PCR, immunoassays, gene silencing, gene expression, etc.), and cell
microscopy). Granted with an international postdoctoral scholarship from ARC Fondation
(France), I am currently
working on the application of biogenic extracellular vesicles and nanoghosts in cancer
theranosis, a cutting-edge,
exciting and fast-growing field.